Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.44 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.44 |
| ▸ | RPS17 | P08708 | 1/20 | 0.44 |
| ▸ | RPSA | P08865 | 1/20 | 0.44 |
| ▸ | RPS2 | P15880 | 1/20 | 0.44 |
| ▸ | RPL35A | P18077 | 1/20 | 0.44 |
| ▸ | RPL7 | P18124 | 1/20 | 0.44 |
| ▸ | RPL17 | P18621 | 1/20 | 0.44 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.44 |
| ▸ | RPS3 | P23396 | 1/20 | 0.44 |
| ▸ | RPS12 | P25398 | 1/20 | 0.44 |
| ▸ | RPL13 | P26373 | 1/20 | 0.44 |
| ▸ | RPL10 | P27635 | 1/20 | 0.44 |
| ▸ | RPL12 | P30050 | 1/20 | 0.44 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 1/20 | 0.44 |
| ▸ | RPL22 | P35268 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007230 | 0.92 | HTR1A (0.63) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4004752 | 0.88 | HTR1A (0.68) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4013639 | 0.88 | HTR1A (0.67) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13770274 | 0.87 | HTR1A (0.61) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4010756 | 0.86 | HTR1A (0.55) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4007428 | 0.85 | HTR1A (0.65) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4008285 | 0.85 | HTR1A (0.64) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4010829 | 0.81 | HTR1A (0.67) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4003945 | 0.80 | HTR1A (0.56) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13769620 | 0.80 | HTR1A (1.00) | HTR1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |