Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007428 | 0.91 | HTR1A (0.65) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4009573 | 0.90 | HTR1A (0.54) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL4006159 | 0.90 | HTR1A (0.66) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL4004752 | 0.87 | HTR1A (0.68) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4007230 | 0.87 | HTR1A (0.63) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4010232 | 0.87 | HTR1A (0.63) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL4010829 | 0.87 | HTR1A (0.67) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4011595 | 0.86 | HTR1A (0.64) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL13770041 | 0.86 | HTR1A (0.58) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL4013180 | 0.86 | P2RY1 (0.49) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |