Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.64 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009215 | 0.91 | HTR1A (0.65) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4003936 | 0.88 | HTR1A (0.66) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4004459 | 0.87 | HTR1A (0.52) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4010232 | 0.87 | HTR1A (0.63) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL4010653 | 0.87 | HTR1A (0.53) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4008285 | 0.86 | HTR1A (0.64) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL4007303 | 0.85 | HTR1A (0.49) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL4167133 | 0.84 | HTR1A (0.62) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL4014513 | 0.84 | PDE10A (0.47) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL4013180 | 0.84 | P2RY1 (0.49) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |