Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014684 | 0.88 | PDE10A (0.56) | PDE10AALDH1A1SMN1; SMN2 | |
| SCHEMBL3321688 | 0.82 | PDE10A (0.54) | PDE10A | |
| SCHEMBL4010869 | 0.81 | PDE10A (0.46) | PDE10ATRPV1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13685571 | 0.81 | PDE10A (0.61) | PDE10A | |
| SCHEMBL16992066 | 0.79 | PDE10A (0.46) | PDE10AALDH1A1SMN1; SMN2 | |
| SCHEMBL4949303 | 0.79 | TRPV1 (0.45) | TRPV1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4007261 | 0.79 | PDE10A (0.46) | PDE10A | |
| SCHEMBL4010237 | 0.78 | PDE10A (0.44) | PDE10ATRPV1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4015332 | 0.78 | PDE10A (0.51) | PDE10AALDH1A1SMN1; SMN2 | |
| SCHEMBL4010759 | 0.78 | TRPV1 (0.43) | PDE10ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |