Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010869 | 0.91 | PDE10A (0.46) | TRPV1PDE10A | |
| SCHEMBL13770042 | 0.89 | PDE10A (0.53) | PDE10A | |
| SCHEMBL4017987 | 0.88 | PDE10A (0.45) | TRPV1PDE10A | |
| SCHEMBL4007141 | 0.80 | PDE10A (0.42) | TRPV1PDE10A | |
| SCHEMBL4015332 | 0.80 | PDE10A (0.51) | PDE10A | |
| SCHEMBL4006732 | 0.80 | PDE10A (0.49) | PDE10A | |
| SCHEMBL4008377 | 0.80 | PDE10A (0.58) | PDE10A | |
| SCHEMBL4014482 | 0.79 | PDE10A (0.44) | TRPV1PDE10A | |
| SCHEMBL4555950 | 0.79 | PDE10A (0.44) | TRPV1PDE10A | |
| SCHEMBL4011858 | 0.79 | PDE10A (0.44) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |