Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.46 |
| ▸ | CDK9 | P50750 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013658 | 0.90 | CCNT1 (0.47) | CCNT1CDK9 | |
| SCHEMBL4010834 | 0.89 | PDE10A (0.47) | PDE10ACCNT1CDK9ALDH1A1SMN1; SMN2 | |
| SCHEMBL16992066 | 0.89 | PDE10A (0.46) | PDE10ACCNT1CDK9ALDH1A1SMN1; SMN2 | |
| SCHEMBL4009648 | 0.87 | CCNT1 (0.46) | PDE10ACCNT1CDK9 | |
| SCHEMBL4007141 | 0.87 | PDE10A (0.42) | PDE10ACCNT1CDK9MAPT | |
| SCHEMBL4013425 | 0.87 | PDE10A (0.62) | PDE10AGRM5GRM1 | |
| SCHEMBL4014684 | 0.86 | PDE10A (0.56) | PDE10AALDH1A1SMN1; SMN2GRM5 | |
| SCHEMBL4006732 | 0.86 | PDE10A (0.49) | PDE10ACCNT1CDK9ALDH1A1SMN1; SMN2 | |
| SCHEMBL4010869 | 0.85 | PDE10A (0.46) | PDE10AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4017987 | 0.84 | PDE10A (0.45) | PDE10AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |