Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL396031 | 0.96 | POLB (0.33) | POLBSERPINE1 | |
| Hydrochloric Acid SCHEMBL5079502 | 0.94 | KCNK9 (0.35) | NR1H4KCNK9 | |
| Hydrochloric Acid SCHEMBL545120 | 0.94 | KCNK9 (0.32) | KCNK9 | |
| Hydrochloric Acid SCHEMBL399755 | 0.93 | GRM5 (0.32) | PPARGNR1H4 | |
| Hydrochloric Acid SCHEMBL401301 | 0.92 | POLB (0.31) | POLB | |
| Hydrochloric Acid SCHEMBL397055 | 0.92 | PPARG (0.32) | PPARGNR1H4POLBSERPINE1 | |
| Hydrochloric Acid SCHEMBL5081233 | 0.91 | KCNK9 (0.31) | NR1H4KCNK9 | |
| Hydrochloric Acid SCHEMBL400914 | 0.90 | PPARG (0.31) | PPARGNR1H4 | |
| Hydrochloric Acid SCHEMBL2863590 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL398948 | 0.89 | MAPT (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4011963-B1 | POLYPROPYLENE RESIN COMPOSITION AND MONOLAYER AND MULTILAYER FILM | MITSUI CHEMICALS INC (JP) | 2024-03-13 | — | — | EP | disclosed |
| EP-4011963-A1 | POLYPROPYLENE RESIN COMPOSITION AND MONOLAYER AND MULTILAYER FILM | Mitsui Chemicals, Inc. (JP) | 2022-06-15 | — | — | EP | disclosed |
| EP-3489298-A1 | POLYPROPYLENE RESIN COMPOSITION AND SINGLE LAYER AND MULTILAYER FILM | Mitsui Chemicals, Inc. (JP) | 2019-05-29 | — | — | EP | disclosed |
| US-20160280819-A1 | CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE-BASED COPOLYMER, PROPYLENE POLYMER, PROPYLENE-BASED POLYMER COMPOSITION, AND USE OF THOSE | MITSUI CHEMICALS, INC. (JP) | 2016-09-29 | — | — | US | disclosed |
| US-9382356-B2 | Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those | MITSUI CHEMICALS, INC. (JP) | 2016-07-05 | — | — | US | disclosed |
| US-8101684-B2 | Thermoplastic resin composition for sealing solar cell, sheet for sealing solar cell and solar cell | MITSUI CHEMICALS, INC. (JP) | 2012-01-24 | — | — | US | disclosed |
| EP-2275457-A2 | Propylene polymer, propylene-based polymer composition, and use of these | Mitsui Chemicals, Inc. (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-7863368-B2 | Propylene resin composition, process for producing propylene resin composition, propylene polymer composition, shaped article produced of the propylene resin composition, and electric wire | MITSUI CHEMICALS, INC. (JP) | 2011-01-04 | — | — | US | disclosed |
| US-20100056691-A1 | PROPYLENE RESIN COMPOSITION, PROCESS FOR PRODUCING PROPYLENE RESIN COMPOSITION, PROPYLENE POLYMER COMPOSITION, SHAPED ARTICLE PRODUCED OF THE PROPYLENE RESIN COMPOSITION, AND ELECTRIC WIRE | MITSUI CHEMICALS, INC. | 2010-03-04 | — | — | US | disclosed |
| US-20100000600-A1 | THERMOPLASTIC RESIN COMPOSITION FOR SEALING SOLAR CELL, SHEET FOR SEALING SOLAR CELL AND SOLAR CELL | MITSUI CHEMICALS, INC. | 2010-01-07 | — | — | US | disclosed |
| EP-2085420-A1 | POLYPROPYLENE RESIN FILM AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2009-08-05 | — | — | EP | disclosed |
| EP-2048194-A1 | THERMOPLASTIC RESIN COMPOSITION FOR SOLAR CELL SEALING, SHEET FOR SOLAR CELL SEALING, AND SOLAR CELL | Mitsui Chemicals, Inc. (JP) | 2009-04-15 | — | — | EP | disclosed |
| US-20080220193-A1 | Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those | MITSUI CHEMICALS, INC. | 2008-09-11 | — | — | US | disclosed |