Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5079502 | 0.98 | KCNK9 (0.35) | KCNK9ACHENPC1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL5081233 | 0.95 | KCNK9 (0.31) | KCNK9 | |
| Hydrochloric Acid SCHEMBL400893 | 0.94 | PPARG (0.33) | KCNK9 | |
| Hydrochloric Acid SCHEMBL2863590 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL399755 | 0.93 | GRM5 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5080454 | 0.92 | NR4A1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL399900 | 0.92 | ACHE (0.36) | ACHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL452699 | 0.91 | NPC1 (0.31) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL2114047 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL2867600 | 0.90 | KCNK3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003739-B2 | Multi-component catalyst systems and polymerization processes for forming in-situ heterophasic copolymers and/or varying the xylene solubles content of polyolefins | FINA TECHNOLOGY, INC. (US) | 2011-08-23 | — | — | US | claimed |
| JP-2009535454-A | — | — | 2009-10-01 | — | — | JP | claimed |
| EP-2013242-A4 | PROCESS FOR COPOLYMER PRODUCTION USING FLUORINATED TRANSITION METAL CATALYSTS | FINA TECHNOLOGY (US) | 2009-08-05 | — | — | EP | claimed |
| EP-2013242-A2 | PROCESS FOR COPOLYMER PRODUCTION USING FLUORINATED TRANSITION METAL CATALYSTS | Fina Technology, Inc. (US) | 2009-01-14 | — | — | EP | claimed |
| WO-2007127414-A2 | PROCESS FOR COPOLYMER PRODUCTION USING FLUORINATED TRANSITION METAL CATALYSTS | FINA TECHNOLOGY, INC. (US) | 2007-11-08 | — | — | WO | claimed |
| US-20070255023-A1 | Process for copolymer production using fluorinated transition metal catalysts | FINA TECHNOLOGY, INC. (US) | 2007-11-01 | — | — | US | claimed |
| US-20070254801-A1 | Fluorinated transition metal catalysts and large scale formation thereof | FINA TECHNOLOGY, INC. (US) | 2007-11-01 | — | — | US | claimed |
| US-11964447-B2 | Laminate | MITSUI CHEMICALS, INC. (JP) | 2024-04-23 | — | — | US | disclosed |
| US-11905348-B2 | Ethylene/alpha-olefin/non-conjugated polyene copolymer, method for producing the same, and use thereof | MITSUI CHEMICALS, INC. (JP) | 2024-02-20 | — | — | US | disclosed |
| EP-3124506-B1 | OLEFIN RESIN AND METHOD FOR PRODUCING SAME | MITSUI CHEMICALS INC (JP) | 2022-06-22 | — | — | EP | disclosed |
| US-10975223-B2 | Resin composition and use thereof | MITSUI CHEMICALS, INC. (JP) | 2021-04-13 | — | — | US | disclosed |
| US-20210009730-A1 | ETHYLENE/alpha-OLEFIN/NON-CONJUGATED POLYENE COPOLYMER, METHOD FOR PRODUCING THE SAME, AND USE THEREOF | MITSUI CHEMICALS, INC. (JP) | 2021-01-14 | — | — | US | disclosed |
| EP-3231842-B1 | PROPYLENE-BASED RESIN COMPOSITION | MITSUI CHEMICALS INC (JP) | 2020-03-11 | — | — | EP | disclosed |
| US-20120095174-A1 | Fluorinated Catalyst Systems and Methods of Forming the Same | FINA TECHNOLOGY, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| US-8110518-B2 | Fluorinated transition metal catalysts and formation thereof | FINA TECHNOLOGY, INC. (US) | 2012-02-07 | — | — | US | disclosed |
| US-7795194-B2 | Synthetic lubricating oil and lubricating oil composition | MITSUI CHEMICALS, INC. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20090156761-A1 | Fluorinated transition metal catalysts and formation thereof | FINA TECHNOLOGY, INC. (US) | 2009-06-18 | — | — | US | disclosed |
| US-7393965-B2 | Crosslinked metallocene compound for olefin polymerization and method of polymerizing olefin with the same | MITSUI CHEMICALS, INC. (JP) | 2008-07-01 | — | — | US | disclosed |
| US-20060116303-A1 | decene-ethylene copolymer, zirconium, titanium or hafnium fluorene-containing complexes, organometallics; improved high thermal oxidation stability, viscosity index, low-temperature viscosity properties and shear stability | MITSUI CHEMICALS, INC. (JP) | 2006-06-01 | — | — | US | disclosed |
| EP-1661921-A1 | Synthetic lubricating oil and lubricating oil composition thereof | Mitsui Chemicals, Inc. (JP) | 2006-05-31 | — | — | EP | disclosed |