Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007237 | 0.92 | TP53 (0.50) | POLBMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL4009495 | 0.86 | TP53 (0.45) | POLBMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL13843270 | 0.85 | TP53 (0.44) | POLBMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL4014947 | 0.82 | AURKA (0.48) | MAPK1CA12CA1CA2CA9 | |
| SCHEMBL4014927 | 0.82 | AURKA (0.48) | MAPK1CA12CA1CA2CA9 | |
| SCHEMBL13843257 | 0.76 | NPC1 (0.51) | POLBMEN1KMT2AMAPTCA12 | |
| SCHEMBL304437 | 0.76 | POLB (0.63) | POLBMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL4009454 | 0.75 | CHRNA7 (0.53) | MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4008595 | 0.75 | PDE4B (0.43) | POLBMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL4143822 | 0.74 | JAK3 (0.48) | POLBMEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534421-B2 | s-Triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof | L'OREAL (FR) | 2009-05-19 | — | — | US | disclosed |
| US-20040258636-A1 | Novel s-triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof | SOCIETE L'OREAL S.A. (FR) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040258636-A1 | Novel s-triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof | TYR, KRT18, TST | POLB 1024/4885MEN1 4041/4885KMT2A 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.