SCHEMBL304437

SCHEMBL304437

O=C(O)c1ccc(Nc2nc(Cl)nc(Nc3ccc(C(=O)O)cc3)n2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.63
MAPT P10636 3/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
MAPK1 P28482 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
CACNA1B Q00975 1/20 0.58
APBA1 Q02410 1/20 0.58
NFKB1 P19838 2/20 0.56
AURKA O14965 3/20 0.55
RHOA P61586 1/20 0.54
PDE4B Q07343 4/20 0.53
LMNA P02545 1/20 0.53
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA9 Q16790 2/20 0.53
PDE4D Q08499 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4094573 0.96 NFKB1 (0.61) POLBMAPTMEN1KMT2AMAPK1
SCHEMBL3793508 0.92 POLB (0.59) POLBMAPTMEN1KMT2AMAPK1
SCHEMBL1023029 0.91 NPC1 (0.71) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL29874885 0.89 NPC1 (0.69) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL4569980 0.85 RHOA (0.72) MAPTMEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL24942659 0.85 AURKA (0.59) SMN1; SMN2NPC1RAB9AAURKAPDE4B
SCHEMBL13852882 0.84 POLB (0.61) POLBMAPTMEN1KMT2AMAPK1
SCHEMBL12998766 0.82 GAA (0.61) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL18516810 0.82 NPC1 (0.68) POLBMAPTMEN1KMT2AMAPK1
SCHEMBL17212282 0.82 NPC1 (0.68) POLBMAPTMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11084959-B2 Curable compositions including a chromonic network, articles, and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-08-10 US disclosed
US-20200347278-A1 CURABLE COMPOSITIONS INCLUDING A CHROMONIC NETWORK, ARTICLES, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY 2020-11-05 US disclosed
CN-107522847-B Chromonic networks in heat-activated curable compositions, articles, and methods 3M创新有限公司 2020-05-15 CN disclosed
EP-1976793-B1 METHOD FOR MAKING NANOSTRUCTURES WITH CHROMONICS 3M INNOVATIVE PROPERTIES CO (US) 2015-02-25 EP disclosed
CN-101939698-B Methods for making electronic devices 3M INNOVATIVE PROPERTIES CO 2014-09-17 CN disclosed
US-8767133-B2 Optical control devices and methods of making 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-07-01 US disclosed
EP-2171018-B1 METHOD FOR FORMING CHANNEL PATTERNS WITH CHROMONIC MATERIALS 3M INNOVATIVE PROPERTIES CO (US) 2014-01-22 EP disclosed
EP-1962915-B1 SILVER ION RELEASING ARTICLES AND METHODS OF MANUFACTURE 3M INNOVATIVE PROPERTIES CO (US) 2013-08-14 EP disclosed
US-8372190-B2 Ink set, inkjet recording method and recorded material FUJIFILM CORPORATION (JP) 2013-02-12 US disclosed
CN-101325980-B Silver ion releasing articles and methods of manufacture 3M INNOVATIVE PROPERTIES CO 2012-10-03 CN disclosed
US-6245399-B1 CONTAINING DICHROIC LAYER 3M INNOVATIVE PROPERTIES COMPANY 2001-06-12 US disclosed
WO-2001035161-A1 LIQUID CRYSTAL ALIGNMENT STRUCTURES AND OPTICAL DEVICES CONTAINING SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-05-17 WO disclosed
EP-1003821-A1 ANISOTROPIC RETARDATION LAYERS FOR DISPLAY DEVICES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-05-31 EP disclosed
WO-2000022463-A1 GUEST-HOST POLARIZERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-04-20 WO disclosed
US-6051290-A Anisotropic retardation layers for display devices 3M INNOVATIVE PROPERTIES COMPANY 2000-04-18 US disclosed
US-5948487-A Anisotropic retardation layers for display devices 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-09-07 US disclosed
WO-1999013021-A1 ANISOTROPIC RETARDATION LAYERS FOR DISPLAY DEVICES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-03-18 WO disclosed
EP-0451228-B1 BRIGHTENING AND LIGHT-STABILIZING SALTS SANDOZ AG (DE) 1994-12-28 EP disclosed
US-5037448-A Processes for the mass dyeing of synthetic polyamides SANDOZ LTD. (CH) 1991-08-06 US disclosed
WO-1991004987-A1 BRIGHTENING AND LIGHT-STABILIZING SALTS SANDOZ LTD. (CH) 1991-04-18 WO disclosed