Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239112 | 0.84 | HPGD (0.65) | HPGDTSHRALDH1A1MAPTNPSR1 | |
| SCHEMBL8222746 | 0.81 | HPGD (0.61) | HPGDTSHRALDH1A1MAPTNPSR1 | |
| SCHEMBL735675 | 0.81 | TSHR (0.81) | HPGDTSHRALDH1A1POLB | |
| SCHEMBL28949192 | 0.81 | HPGD (0.68) | HPGDTSHRALDH1A1MAPTNPSR1 | |
| SCHEMBL12424630 | 0.81 | POLB (0.74) | HPGDTSHRALDH1A1MAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL4438395 | 0.80 | HPGD (0.59) | HPGDTSHRALDH1A1MAPTNPSR1 | |
| SCHEMBL1983277 | 0.79 | HPGD (0.63) | HPGDTSHRALDH1A1MAPTNPSR1 | |
| SCHEMBL3939129 | 0.79 | NPSR1 (0.69) | HPGDTSHRALDH1A1MAPTNPSR1 | |
| Hydrazine SCHEMBL28119021 | 0.78 | TSHR (0.89) | HPGDTSHRALDH1A1MAPTPOLB | |
| SCHEMBL1714894 | 0.78 | HPGD (0.57) | HPGDTSHRALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041112-A1 | NEW PYRIDINE ANALOGUES | Astra Zeneca AB (SE) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008004941-A1 | NEW PYRIDINE ANALOGUES | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | WO | disclosed |