Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 16/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4209536 | 0.84 | GPR119 (0.43) | — | |
| SCHEMBL4337461 | 0.83 | HTR2A (0.48) | HTR2AHTR2C | |
| SCHEMBL4248885 | 0.79 | HTR2C (0.53) | HTR2AHTR2CDGAT2 | |
| SCHEMBL4212899 | 0.77 | KDM4E (0.46) | HTR2AHTR2C | |
| SCHEMBL4204478 | 0.76 | HTR2C (0.63) | HTR2AHTR2C | |
| SCHEMBL4208588 | 0.75 | MAP4K4 (0.45) | HTR2AHTR2C | |
| SCHEMBL4209618 | 0.74 | GPR119 (0.43) | — | |
| SCHEMBL4010625 | 0.74 | HTR2A (0.41) | HTR2AHTR2C | |
| SCHEMBL4011215 | 0.70 | GRM5 (0.36) | — | |
| SCHEMBL4215873 | 0.70 | MAP4K4 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079765-A1 | COMPOUNDS WITH ACTIVITY AT THE 5-HT2C RECEPTOR | CASCADE THERAPEUTICS INC. (CA) | 2009-07-02 | — | — | WO | disclosed |