Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 3/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28289385 | 1.00 | KDM4E (0.50) | KDM4ECYP3A4LMNATSHRNAAA | |
| SCHEMBL2405138 | 0.99 | KDM4E (0.51) | KDM4ECYP3A4LMNATSHRNAAA | |
| SCHEMBL2998832 | 0.88 | KDM4E (0.64) | KDM4ECYP3A4LMNATSHRCYP1A2 | |
| SCHEMBL29038561 | 0.85 | LMNA (0.56) | KDM4ECYP3A4LMNATSHRNAAA | |
| SCHEMBL29038570 | 0.85 | LMNA (0.56) | KDM4ECYP3A4LMNATSHRNAAA | |
| SCHEMBL31313418 | 0.84 | KDM5A (0.56) | KDM4ECYP3A4LMNATSHRKDM5A | |
| SCHEMBL29184940 | 0.84 | KDM5A (0.56) | KDM4ECYP3A4LMNATSHRKDM5A | |
| SCHEMBL3122441 | 0.84 | KDM5A (0.56) | KDM4ECYP3A4LMNATSHRKDM5A | |
| SCHEMBL3630367 | 0.84 | KDM4E (0.58) | KDM4ECYP3A4LMNATSHRNAAA | |
| SCHEMBL31313484 | 0.84 | KDM5A (0.56) | KDM4ECYP3A4LMNATSHRKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2068873-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | Pharma 2100 (DK) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008031440-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | PHARMA 2100 (DK) | 2008-03-20 | — | — | WO | disclosed |