Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRLHR | P49683 | 3/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.37 |
| ▸ | LIPE | Q05469 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13962543 | 0.90 | SMN1; SMN2 (0.37) | PRLHRPTGDR2LIPEHPGDMAPT | |
| SCHEMBL4015621 | 0.89 | TIPARP (0.37) | PRLHRLIPEHPGDMAPTSMN1; SMN2 | |
| SCHEMBL4012751 | 0.88 | PTGDR2 (0.40) | PTGDR2NPSR1HPGDMAPTHTT | |
| SCHEMBL4005110 | 0.88 | HPGD (0.43) | PTGDR2NPSR1HPGDMAPTHTT | |
| SCHEMBL4013090 | 0.87 | TAAR1 (0.39) | PTGDR2NPSR1HPGDMAPTHTT | |
| SCHEMBL4014897 | 0.85 | NPSR1 (0.47) | PTGDR2NPSR1HPGDMAPTHTT | |
| SCHEMBL13963195 | 0.84 | NPSR1 (0.40) | PRLHRPTGDR2NPSR1HPGDMAPT | |
| SCHEMBL4008415 | 0.84 | MAPT (0.41) | PTGDR2NPSR1HPGDMAPTHTT | |
| SCHEMBL4015878 | 0.84 | HPGD (0.36) | PTGDR2NPSR1HPGDMAPTHTT | |
| SCHEMBL4010141 | 0.83 | KMT2A (0.39) | PTGDR2NPSR1HPGDMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |