Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13963195 | 0.92 | NPSR1 (0.40) | NPSR1MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13962555 | 0.89 | MAPT (0.43) | NPSR1MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4010032 | 0.85 | PRLHR (0.38) | NPSR1MAPTSMN1; SMN2HTTPTGDR2 | |
| SCHEMBL3935772 | 0.84 | PTGDR2 (0.38) | NPSR1MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4016104 | 0.83 | AGBL2 (0.41) | NPSR1MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4006857 | 0.81 | HPGD (0.41) | NPSR1MAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL13962550 | 0.81 | MAPT (0.37) | NPSR1MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13963196 | 0.81 | HPGD (0.37) | NPSR1MAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4011125 | 0.80 | ALDH1A1 (0.37) | NPSR1MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13963194 | 0.78 | PTGDR2 (0.43) | NPSR1MAPTHTTPTGDR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |