Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472002 | 0.85 | HTR2A (0.48) | MAPTALDH1A1GAASMN1; SMN2HTR1A | |
| SCHEMBL6065302 | 0.83 | CYP2C9 (0.51) | MAPTALDH1A1GAASMN1; SMN2HTR1A | |
| SCHEMBL3919075 | 0.82 | HRH1 (0.42) | MAPTALDH1A1GAASMN1; SMN2HTR1A | |
| SCHEMBL4009513 | 0.81 | GRM5 (0.47) | MAPTALDH1A1SMN1; SMN2POLBMEN1 | |
| SCHEMBL3720029 | 0.79 | KDM4E (0.45) | MAPTKDM4EPOLBLMNA | |
| SCHEMBL3917828 | 0.79 | MAPT (0.43) | MAPTALDH1A1GAASMN1; SMN2HTR1A | |
| SCHEMBL5698823 | 0.76 | SMN1; SMN2 (0.41) | MAPTALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL4710630 | 0.75 | MAPT (0.51) | MAPTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL3917775 | 0.74 | SMN1; SMN2 (0.47) | MAPTALDH1A1GAASMN1; SMN2HTR1A | |
| SCHEMBL3916322 | 0.74 | HRH1 (0.45) | MAPTALDH1A1GAASMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080675-A1 | QUINOLINE DERIVATIVES WITH AFFINITY FOR THE 5-HT2B RECEPTOR | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |