Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | SLC33A1 | O00400 | 6/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302459 | 0.90 | AGTR1 (0.52) | AGTR1PPARGSLC33A1 | |
| SCHEMBL4016594 | 0.86 | SLC33A1 (0.54) | AGTR1PPARGSLC33A1 | |
| SCHEMBL4011449 | 0.85 | SLC33A1 (0.53) | AGTR1PPARGSLC33A1 | |
| SCHEMBL4011388 | 0.83 | PPARG (0.49) | AGTR1PPARGSLC33A1 | |
| SCHEMBL4305728 | 0.83 | PPARG (0.53) | AGTR1PPARG | |
| SCHEMBL4012946 | 0.83 | SLC33A1 (0.51) | AGTR1PPARGSLC33A1 | |
| SCHEMBL4011112 | 0.83 | PPARG (0.53) | AGTR1PPARGSLC33A1 | |
| SCHEMBL4312419 | 0.81 | PPARG (0.48) | AGTR1PPARGSLC33A1 | |
| SCHEMBL4009430 | 0.81 | PPARG (0.49) | AGTR1PPARGSLC33A1 | |
| SCHEMBL4016688 | 0.79 | PPARG (0.47) | AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |