Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012119 | 0.90 | FAAH (0.79) | FAAHLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3934606 | 0.89 | FAAH (0.80) | FAAHLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4014297 | 0.88 | FAAH (0.76) | FAAHLMNASMN1; SMN2 | |
| SCHEMBL3941337 | 0.87 | FAAH (0.77) | FAAHLMNAMAPT | |
| SCHEMBL4013756 | 0.86 | FAAH (0.81) | FAAHLMNASMN1; SMN2MAPT | |
| SCHEMBL3933960 | 0.85 | FAAH (0.86) | FAAHLMNASMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL3942978 | 0.85 | FAAH (0.86) | FAAHLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3939612 | 0.84 | FAAH (0.83) | FAAHLMNAALDH1A1 | |
| SCHEMBL3932480 | 0.84 | FAAH (0.83) | FAAHLMNAALDH1A1MAPT | |
| SCHEMBL3930701 | 0.84 | FAAH (0.86) | FAAHLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |