Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018971 | 0.91 | FAAH (0.76) | FAAH | |
| SCHEMBL4015887 | 0.91 | FAAH (0.76) | FAAHKDM4EL3MBTL1AKR1C3TSHR | |
| SCHEMBL3934606 | 0.90 | FAAH (0.80) | FAAHKMT2AMEN1AKR1C3AKR1C2 | |
| SCHEMBL4017908 | 0.89 | FAAH (0.72) | FAAHAKR1C3SMN1; SMN2 | |
| SCHEMBL4010751 | 0.88 | FAAH (0.85) | FAAHAKR1C3AKR1C2 | |
| SCHEMBL4010314 | 0.88 | FAAH (0.71) | FAAHLMNASMN1; SMN2 | |
| SCHEMBL4008348 | 0.87 | FAAH (0.68) | FAAH | |
| SCHEMBL3933960 | 0.87 | FAAH (0.86) | FAAHLMNASMN1; SMN2 | |
| SCHEMBL3942978 | 0.87 | FAAH (0.86) | FAAHPKMTSHRLMNASMN1; SMN2 | |
| SCHEMBL3941135 | 0.87 | FAAH (1.00) | FAAHKMT2AMEN1AKR1C3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |