Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892529 | 0.86 | PPARG (0.48) | PPARGAGTR1ACHEDPP4GRIN1 | |
| SCHEMBL4010946 | 0.82 | PPARG (0.56) | PPARGAGTR1ACHE | |
| SCHEMBL4013553 | 0.82 | PPARG (0.49) | PPARGACHEDPP4GRIN1GRIN2B | |
| SCHEMBL1887400 | 0.82 | PPARG (0.51) | PPARGAGTR1ACHEDPP4GRIN1 | |
| SCHEMBL1890010 | 0.80 | PPARG (0.48) | PPARGACHEDPP4GRIN1GRIN2B | |
| SCHEMBL30289434 | 0.78 | PPARG (0.70) | PPARGAGTR1ALOX5APCNR2 | |
| SCHEMBL4013349 | 0.77 | PPARG (0.41) | PPARGACHEDPP4GRIN1GRIN2B | |
| SCHEMBL4010668 | 0.75 | PPARG (0.63) | PPARGAGTR1ACHE | |
| SCHEMBL1895341 | 0.75 | PPARG (0.48) | PPARGACHEDPP4GRIN1GRIN2B | |
| SCHEMBL1886369 | 0.74 | PPARG (0.64) | PPARGAGTR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |