Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1895341 | 0.89 | PPARG (0.48) | PPARGALOX5APP2RX3MEN1KMT2A | |
| SCHEMBL4010868 | 0.87 | PPARG (0.55) | PPARGALDH1A1MAPK1P2RX3ACHE | |
| SCHEMBL4014913 | 0.86 | PPARG (0.49) | PPARGACHE | |
| SCHEMBL4010316 | 0.82 | PPARG (0.48) | PPARGALOX5APACHEGRIN1GRIN2B | |
| SCHEMBL4016615 | 0.80 | PPARG (0.54) | PPARGACHE | |
| SCHEMBL1889717 | 0.79 | PPARG (0.56) | PPARGACHE | |
| SCHEMBL1890010 | 0.78 | PPARG (0.48) | PPARGALOX5APACHEFFAR1AKR1B1 | |
| SCHEMBL1890245 | 0.78 | PPARG (0.50) | PPARGACHE | |
| SCHEMBL4014315 | 0.78 | PPARG (0.44) | PPARGALDH1A1MAPK1P2RX3GRIN1 | |
| SCHEMBL4013349 | 0.78 | PPARG (0.41) | PPARGALOX5APACHEGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |