Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886815 | 0.90 | PPARG (0.42) | PPARGTNIKGRM2ALOX5APCNR2 | |
| SCHEMBL4010039 | 0.81 | PPARG (0.45) | PPARGACHE | |
| SCHEMBL4013210 | 0.79 | PPARG (0.43) | PPARGACHE | |
| SCHEMBL2879858 | 0.78 | PPARG (0.45) | PPARGACHE | |
| SCHEMBL4013553 | 0.78 | PPARG (0.49) | PPARGALOX5APACHEGRIN1GRIN2B | |
| SCHEMBL1886738 | 0.77 | PPARG (0.46) | PPARGACHE | |
| SCHEMBL4010316 | 0.77 | PPARG (0.48) | PPARGALOX5APCNR2ACHEGRIN1 | |
| SCHEMBL1890872 | 0.76 | PPARG (0.48) | PPARG | |
| SCHEMBL1887400 | 0.73 | PPARG (0.51) | PPARGALOX5APACHEGRIN1GRIN2B | |
| SCHEMBL4013058 | 0.73 | PPARG (0.46) | PPARGTNIKACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |