SCHEMBL4010567

SCHEMBL4010567

C=C(C)C(=O)OCCOP(=O)(OCCOC(=O)C(=C)C)OP(=O)(OCCOC(=O)C(=C)C)OCCOC(=O)C(=C)C

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.53
TSHR P16473 4/20 0.47
ALDH1A1 P00352 2/20 0.42
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
BTN3A1 O00481 1/20 0.34
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CYP3A4 P08684 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL41530 0.92 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL345559 0.91 THRB (0.49) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL4001460 0.90 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
Phosphoric Acid SCHEMBL18787889 0.89 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2641079 0.87 THRB (0.61) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3274864 0.87 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3680829 0.87 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL846315 0.85 THRB (0.59) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3899254 0.85 THRB (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16574839 0.85 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2853253-B1 Dental curable composition containing particles with different refractive indexes SHOFU INC (JP) 2022-04-27 EP disclosed
US-9511005-B2 Dental curable composition containing particles with different refractive indexes SHOFU INC. (JP) 2016-12-06 US disclosed
US-9066852-B2 Dental adhesive primer composition KABUSHIKI KAISHA SHOFU (JP) 2015-06-30 US disclosed
US-20150094396-A1 DENTAL CURABLE COMPOSITION CONTAINING PARTICLES WITH DIFFERENT REFRACTIVE INDEXES SHOFU INC. (JP) 2015-04-02 US disclosed
EP-2853253-A2 Dental curable composition containing particles with different refractive indexes Shofu Inc. (JP) 2015-04-01 EP disclosed
US-20090299006-A1 Dental Adhesive Primer Composition KABUSHIKI KAISHA SHOFU (JP) 2009-12-03 US disclosed
US-7488762-B2 Two paste-type glass ionomer cement KABUSHIKI KAISHA SHOFU (JP) 2009-02-10 US disclosed
US-20060247330-A1 Two paste-type glass ionomer cement KABUSHIKI KAISHA SHOFU (JP) 2006-11-02 US disclosed
US-4292235-A WATERPROOFING, METHYL METHACRYLATE COPOLYMER, PENTAVALENT PHOSPHORUS COMPOUND MITSUI TOATSU CHEMICALS, INC. (JP) 1981-09-29 US disclosed