Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41530 | 0.94 | THRB (0.57) | THRBTSHRCYP3A4ALDH1A1POLB | |
| SCHEMBL13716858 | 0.93 | THRB (0.64) | THRBTSHRCYP3A4ALDH1A1POLB | |
| SCHEMBL14097731 | 0.93 | THRB (0.64) | THRBTSHRCYP3A4ALDH1A1POLB | |
| Phosphoric Acid SCHEMBL18787889 | 0.91 | THRB (0.53) | THRBTSHRCYP3A4ALDH1A1POLB | |
| SCHEMBL4066760 | 0.87 | THRB (0.59) | THRBTSHRCYP3A4ALDH1A1POLB | |
| SCHEMBL4066752 | 0.87 | THRB (0.59) | THRBTSHRCYP3A4ALDH1A1POLB | |
| SCHEMBL6690732 | 0.87 | THRB (0.59) | THRBTSHRCYP3A4ALDH1A1POLB | |
| SCHEMBL22219483 | 0.87 | THRB (0.59) | THRBTSHRCYP3A4ALDH1A1POLB | |
| SCHEMBL4797967 | 0.87 | THRB (0.59) | THRBTSHRCYP3A4ALDH1A1POLB | |
| SCHEMBL846315 | 0.87 | THRB (0.59) | THRBTSHRCYP3A4ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4746543-B2 | — | — | 2011-08-10 | — | — | JP | claimed |
| US-7700668-B2 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2010-04-20 | — | — | US | claimed |
| US-20060270751-A1 | Adhesive composition with decreased polarity upon polymerization | 3M DEUTSCHLAND GMBH (DE) | 2006-11-30 | — | — | US | claimed |
| EP-1498098-B1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2006-05-03 | — | — | EP | claimed |
| WO-2005004819-A1 | ADHESIVE COMPOSITION WITH DECREASED POLARITY UPON POLYMERIZATION | 3M ESPE AG (DE) | 2005-01-20 | — | — | WO | claimed |
| EP-1498098-A1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2005-01-19 | — | — | EP | claimed |
| US-7700668-B2 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2010-04-20 | — | — | US | disclosed |
| EP-1639987-B1 | Dental adhesive composition | 3M ESPE AG (DE) | 2009-08-12 | — | — | EP | disclosed |
| EP-1956058-B1 | Ink composition for inkjet-recording and method for inkjet-recording | FUJIFILM CORP (JP) | 2009-08-12 | — | — | EP | disclosed |
| EP-1956058-A1 | Ink composition for inkjet-recording and method for inkjet-recording | FUJIFILM Corporation (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-20060270751-A1 | Adhesive composition with decreased polarity upon polymerization | 3M DEUTSCHLAND GMBH (DE) | 2006-11-30 | — | — | US | disclosed |
| EP-1498098-B1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2006-05-03 | — | — | EP | disclosed |
| US-20060069181-A1 | Dental adhesive composition | 3M ESPE AG | 2006-03-30 | — | — | US | disclosed |
| EP-1639987-A1 | Dental adhesive composition | 3M Espe AG (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005004819-A1 | ADHESIVE COMPOSITION WITH DECREASED POLARITY UPON POLYMERIZATION | 3M ESPE AG (DE) | 2005-01-20 | — | — | WO | disclosed |
| EP-1498098-A1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2005-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270751-A1 | Adhesive composition with decreased polarity upon polymerization | PTK2, PHOSPHO1, ITGA1 | THRB 3495/4885TSHR 4650/4885CYP3A4 4432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.