Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 12/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008415 | 0.89 | MAPT (0.41) | MAPTPANK3HPGDTSHRSMN1; SMN2 | |
| SCHEMBL4009380 | 0.87 | HPGD (0.39) | MAPTTAAR1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL4009901 | 0.85 | CHRM1 (0.38) | TAAR1 | |
| SCHEMBL13963129 | 0.85 | TAAR1 (0.36) | MAPTTAAR1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL13963125 | 0.83 | TAAR1 (0.35) | MAPTTAAR1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL13962552 | 0.83 | PTGDR2 (0.36) | TAAR1 | |
| SCHEMBL4011802 | 0.82 | TAAR1 (0.39) | MAPTTAAR1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL4015621 | 0.82 | TIPARP (0.37) | MAPTTAAR1HPGDSMN1; SMN2 | |
| SCHEMBL4012393 | 0.82 | TAAR1 (0.34) | MAPTTAAR1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL4006522 | 0.82 | ALDH1A1 (0.38) | MAPTTAAR1PANK3HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |