SCHEMBL4010795

SCHEMBL4010795

C=CC[C@]1(n2cc(N)c(=O)[nH]c2=O)C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 9/20 0.41
P2RY2 P41231 7/20 0.41
POLA1 P09884 2/20 0.39
POLB P06746 1/20 0.39
POLD1 P28340 1/20 0.39
P2RY4 P51582 5/20 0.39
DTYMK P23919 2/20 0.36
P2RX3 P56373 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5285301 0.90 POLB (0.48) P2RY6P2RY2POLA1POLBPOLD1
SCHEMBL3485976 0.87 P2RY6 (0.41) P2RY6P2RY2POLA1POLBPOLD1
SCHEMBL27186873 0.85 POLG (0.41) P2RY6P2RY2P2RY4P2RX3
SCHEMBL4619794 0.85 P2RY6 (0.55) P2RY6P2RY2POLA1P2RY4
SCHEMBL18241039 0.83 P2RY2 (0.44) P2RY6P2RY2POLA1POLBPOLD1
SCHEMBL28836964 0.81 TK1 (0.34)
SCHEMBL5191085 0.80 POLB (0.50) P2RY6P2RY2POLA1POLBPOLD1
SCHEMBL95680 0.77 P2RY6 (0.54) P2RY6P2RY2POLA1P2RY4
SCHEMBL28794808 0.77 P2RX1 (0.53) P2RY2POLBP2RX3
SCHEMBL8440658 0.76 P2RY6 (0.54) P2RY6P2RY2POLA1P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240110237-A1 FUNCTIONAL LIGANDS BASE PAIR BIOTECHNOLOGIES INC (US) 2024-04-04 US disclosed
EP-1725572-B1 MACROMOLECULAR NUCLEOTIDE COMPOUNDS AND METHODS FOR USING THE SAME AGCT GMBH (DE) 2017-05-31 EP disclosed
EP-2074133-A2 COMPONENTS AND METHOD FOR ENZYMATIC SYNTHESIS OF NUCLEIC ACIDS Genovoxx GmbH (DE) 2009-07-01 EP disclosed
WO-2008043426-A2 COMPONENTS AND METHOD FOR ENZYMATIC SYNTHESIS OF NUCLEIC ACIDS GENOVOXX GMBH (DE) 2008-04-17 WO disclosed
EP-1725572-A2 MACROMOLECULAR NUCLEOTIDE COMPOUNDS AND METHODS FOR USING THE SAME Genovoxx GmbH (DE) 2006-11-29 EP disclosed
WO-2005044836-A2 MACROMOLECULAR NUCLEOTIDE COMPOUNDS AND METHODS FOR USING THE SAME GENOVOXX GMBH (DE) 2005-05-19 WO disclosed