⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491417 | 0.85 | — | — | |
| SCHEMBL58386 | 0.78 | — | — | |
| SCHEMBL491394 | 0.78 | — | — | |
| SCHEMBL455963 | 0.74 | — | — | |
| SCHEMBL149391 | 0.74 | — | — | |
| Benzene SCHEMBL8015363 | 0.73 | TSHR (0.44) | — | |
| SCHEMBL8532116 | 0.72 | — | — | |
| SCHEMBL698165 | 0.70 | AHR (0.31) | — | |
| SCHEMBL147500 | 0.69 | ALDH1A1 (0.34) | — | |
| SCHEMBL491558 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |
| US-20070032482-A1 | Benzoxazinone-derived sulfonamide compounds, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 2007-02-08 | — | — | US | claimed |
| EP-1648886-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-04-26 | — | — | EP | claimed |
| WO-2005014589-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE S.A. (DE) | 2005-02-17 | — | — | WO | claimed |
| CN-115244037-A | Substituted triazinones as thyroid hormone receptor agonists | 上海诚益生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| CN-104326952-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| US-9409917-B2 | Heterocyclic amide derivatives as P2X7 receptor antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2016-08-09 | — | — | US | disclosed |
| EP-3045450-A1 | INTERMEDIATE COMPOUNDS IN A PROCESS FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO., LTD. (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-2614053-B1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATES THEREOF | SUMITOMO CHEMICAL CO (JP) | 2016-03-23 | — | — | EP | disclosed |
| EP-2804865-B1 | HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2015-12-23 | — | — | EP | disclosed |
| CN-103180300-B | Process for producing pyridazinone compound and intermediate thereof | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-10-07 | — | — | CN | disclosed |
| US-6174912-B1 | FOR TREATING PSYCHIATRIC DISORDERS AND NEUROLOGICAL DISEASES INCLUDING MAJOR DEPRESSION, ANXIETY-RELATED DISORDERS, POST-TRAUMATIC STRESS DISORDER, SUPRANUCLEAR PALSY AND FEEDING DISORDERS AS WELL AS TREATMENT OF IMMUNOLOGICAL DISEASES | DUPONT PHARMACEUTICALS COMPANY | 2001-01-16 | — | — | US | disclosed |
| US-6090946-A | Process for the preparation of 3-(substituted phenyl)-5-alkylidene-1,3-oxazolidine-2,4-dione derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0937081-A1 | NITROGEN SUBSTITUTED IMIDAZO 4,5-c]PYRAZOLES AS CORTICOTROPIN RELEASING HORMONE ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 1999-08-25 | — | — | EP | disclosed |
| WO-1999010350-A1 | NITROGEN SUBSTITUTED IMIDAZO[4,5-c]PYRAZOLES AS CORTICOTROPIN RELEASING HORMONE ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |
| EP-0637609-B1 | Flame-retardant aromatic polycarbonate resin | TEIJIN CHEMICALS LTD (JP) | 1998-12-09 | — | — | EP | disclosed |
| EP-0812834-A1 | PROCESS FOR THE PREPARATION OF 3-(SUBSTITUTED PHENYL)-5-ALKYLIDENE-1,3-OXAZOLIDINE-2,4-DIONE DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5478874-A | Radiation transparent | TEIJIN CHEMICALS LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0637609-A2 | Flame-retardant aromatic polycarbonate resin | Teijin Chemicals, Ltd. (JP) | 1995-02-08 | — | — | EP | disclosed |