Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
| ▸ | SLC33A1 | O00400 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010280 | 0.84 | PPARG (0.52) | PPARGAGTR1SLC33A1 | |
| SCHEMBL4017109 | 0.78 | AGTR1 (0.46) | PPARGAGTR1SLC33A1 | |
| SCHEMBL1893953 | 0.77 | AGTR1 (0.56) | PPARGAGTR1 | |
| SCHEMBL4016028 | 0.76 | AGTR1 (0.52) | PPARGAGTR1SLC33A1 | |
| SCHEMBL4016469 | 0.75 | PPARG (0.52) | PPARGAGTR1SLC33A1 | |
| SCHEMBL4011200 | 0.73 | LTB4R2 (0.42) | PPARGSLC33A1 | |
| SCHEMBL4309196 | 0.71 | PPARG (0.40) | PPARGAGTR1SLC33A1 | |
| SCHEMBL4016389 | 0.71 | PPARG (0.58) | PPARGAGTR1 | |
| SCHEMBL12349208 | 0.71 | PPARG (0.57) | PPARGAGTR1SLC33A1 | |
| SCHEMBL1892495 | 0.70 | AGTR1 (0.41) | PPARGAGTR1SLC33A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |