Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.52 |
| ▸ | SLC33A1 | O00400 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016469 | 0.91 | PPARG (0.52) | PPARGAGTR1SLC33A1KCNH2 | |
| SCHEMBL4016389 | 0.87 | PPARG (0.58) | PPARGAGTR1KCNH2 | |
| SCHEMBL4011196 | 0.84 | PPARG (0.48) | PPARGAGTR1SLC33A1 | |
| SCHEMBL4016047 | 0.81 | PPARG (0.45) | PPARGAGTR1SLC33A1KCNH2 | |
| SCHEMBL4008048 | 0.81 | SLC33A1 (0.47) | PPARGAGTR1SLC33A1 | |
| SCHEMBL4017109 | 0.80 | AGTR1 (0.46) | PPARGAGTR1SLC33A1 | |
| SCHEMBL4016515 | 0.77 | SLC33A1 (0.47) | PPARGAGTR1SLC33A1 | |
| SCHEMBL4016028 | 0.77 | AGTR1 (0.52) | PPARGAGTR1SLC33A1 | |
| SCHEMBL1895203 | 0.77 | PPARG (0.57) | PPARGAGTR1KCNH2 | |
| SCHEMBL4010601 | 0.76 | AGTR1 (0.45) | PPARGAGTR1SLC33A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |