Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634618 | 0.95 | KCNH2 (0.60) | KCNH2HRH3 | |
| Fumaric Acid SCHEMBL3635098 | 0.88 | KCNH2 (0.53) | KCNH2HRH3 | |
| SCHEMBL4019237 | 0.88 | KCNH2 (0.42) | KCNH2HRH3 | |
| SCHEMBL4011082 | 0.84 | KCNH2 (0.47) | KCNH2HRH3 | |
| SCHEMBL13168150 | 0.74 | KCNH2 (0.61) | KCNH2HRH3 | |
| SCHEMBL12863267 | 0.74 | HRH3 (0.69) | KCNH2HRH3 | |
| SCHEMBL1938186 | 0.73 | KCNH2 (1.00) | KCNH2HRH3 | |
| SCHEMBL1939411 | 0.73 | KCNH2 (1.00) | KCNH2HRH3 | |
| SCHEMBL1939700 | 0.73 | KCNH2 (1.00) | KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL1939605 | 0.72 | KCNH2 (0.98) | KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074086-A1 | BIPHENYL SULFONYL AND PHENYL-HETEROARYL SULFONYL MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008048609-A1 | BIPHENYL SULFONYL AND PHENYL-HETEROARYL SULFONYL MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2008-04-24 | — | — | WO | disclosed |