Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011219 | 0.95 | KCNH2 (0.58) | KCNH2HRH3 | |
| Fumaric Acid SCHEMBL3635098 | 0.93 | KCNH2 (0.53) | KCNH2HRH3 | |
| SCHEMBL4019237 | 0.85 | KCNH2 (0.42) | KCNH2HRH3 | |
| SCHEMBL4011082 | 0.81 | KCNH2 (0.47) | KCNH2HRH3 | |
| SCHEMBL12863267 | 0.80 | HRH3 (0.69) | KCNH2HRH3 | |
| SCHEMBL13168396 | 0.77 | KCNH2 (0.64) | KCNH2HRH3 | |
| SCHEMBL1128396 | 0.75 | KCNH2 (1.00) | KCNH2HRH3 | |
| SCHEMBL1128120 | 0.75 | KCNH2 (1.00) | KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL1141464 | 0.74 | KCNH2 (0.98) | KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL1141460 | 0.74 | KCNH2 (0.98) | KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155668-A2 | CRYSTALLINE FORMS OF (R)-1-{2-Ý4'- (3-METHOXY-PROPANE-1- SULFONYL)-BIPHENYL-4-YL¨-ETHYL}-2-METHYL-PYRROLIDINE, AND COMPOSITIONS, AND METHODS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008153958-A2 | CRYSTALLINE FORMS OF (R)-1-{2-[4'- (3-METHOXY-PROPANE-1- SULFONYL)-BIPHENYL-4-YL]-ETHYL}-2-METHYL-PYRROLIDINE, AND COMPOSITIONS, AND METHODS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2008-12-18 | — | — | WO | disclosed |