Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 8/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890409 | 0.88 | PPARG (0.46) | PPARGMAPK14AGTR1GRIN1GRIN2B | |
| SCHEMBL1892153 | 0.85 | PPARG (0.46) | PPARGMAPK14AGTR1AGTR2 | |
| SCHEMBL1895425 | 0.84 | PPARG (0.48) | PPARGMAPK14AGTR1GRIN1GRIN2B | |
| SCHEMBL4016245 | 0.83 | PPARG (0.47) | PPARGMAPK14AGTR1GRIN1GRIN2B | |
| SCHEMBL4015819 | 0.83 | PPARG (0.41) | PPARGMAPK14AGTR1GRIN1GRIN2B | |
| SCHEMBL4008828 | 0.83 | AGTR1 (0.42) | PPARGAGTR1GRIN1GRIN2BAGTR2 | |
| SCHEMBL4011357 | 0.83 | AGTR1 (0.40) | PPARGMAPK14AGTR1GRIN1GRIN2B | |
| SCHEMBL1890240 | 0.82 | MAPK14 (0.42) | PPARGMAPK14AGTR1AGTR2 | |
| SCHEMBL4010946 | 0.80 | PPARG (0.56) | PPARGAGTR1AGTR2 | |
| SCHEMBL4010555 | 0.79 | PPARG (0.38) | PPARGMAPK14AGTR1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |