Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.38 |
| ▸ | PTGES | O14684 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1894764 | 0.91 | PPARG (0.39) | PPARGGRIN1GRIN2BPTGESMAPK14 | |
| SCHEMBL4015819 | 0.81 | PPARG (0.41) | PPARGGRIN1GRIN2BMAPK14AGTR1 | |
| SCHEMBL4008828 | 0.81 | AGTR1 (0.42) | PPARGGRIN1GRIN2BAGTR1AGTR2 | |
| SCHEMBL4013812 | 0.81 | PPARG (0.39) | PPARGGRIN1GRIN2BAGTR1AGTR2 | |
| SCHEMBL4010582 | 0.80 | PPARG (0.50) | PPARGPTGESAGTR1AGTR2 | |
| SCHEMBL4011357 | 0.80 | AGTR1 (0.40) | PPARGGRIN1GRIN2BMAPK14AGTR1 | |
| SCHEMBL4011554 | 0.79 | PPARG (0.46) | PPARGGRIN1GRIN2BMAPK14AGTR1 | |
| SCHEMBL1889960 | 0.79 | PPARG (0.40) | PPARGGRIN1GRIN2BMAPK14AGTR1 | |
| SCHEMBL1890918 | 0.78 | PPARG (0.51) | PPARGAGTR1 | |
| SCHEMBL4011619 | 0.77 | AGTR1 (0.42) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |