Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811069 | 0.75 | PPIA (0.43) | GPR3HTR2A | |
| SCHEMBL14932067 | 0.72 | — | — | |
| SCHEMBL7003017 | 0.72 | — | — | |
| SCHEMBL29797969 | 0.71 | GPR3 (0.46) | HTR7HTR2BGPR3HTR2A | |
| SCHEMBL4359049 | 0.71 | GPR3 (0.46) | HTR7HTR2BGPR3HTR2A | |
| SCHEMBL6658831 | 0.71 | HTR2A (0.43) | GPR3HTR2A | |
| SCHEMBL7111303 | 0.69 | MEN1 (0.39) | HTR7HTR2BGPR3HTR2A | |
| SCHEMBL25223032 | 0.69 | MEN1 (0.35) | GPR3 | |
| SCHEMBL12887878 | 0.69 | MEN1 (0.35) | GPR3 | |
| SCHEMBL8397577 | 0.69 | MEN1 (0.35) | GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742931-B1 | DIBENZOFURAN, DIBENZOTHIOPHENE AND FLUORENE DERIVATIVES AS COMPONENTS OF LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2014-04-23 | — | — | EP | disclosed |
| US-7514127-B2 | Dibenzofuran derivatives, dibenzothiophene derivatives and fluorene derivatives | MERCK PATENT GMBH (DE) | 2009-04-07 | — | — | US | disclosed |
| US-20070219380-A1 | Dibenzofuran Derivatives, Dibenzothiophene Derivatives and Fluorene Derivatives | MERCK PATENT GMBH (DE) | 2007-09-20 | — | — | US | disclosed |
| EP-1742931-A1 | DIBENZOFURAN DERIVATIVES, DIBENZOTHIOPHENE DERIVATIVES, AND FLUORENE DERIVATIVES | MERCK PATENT GmbH (DE) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005105772-A1 | DIBENZOFURAN DERIVATIVES, DIBENZOTHIOPHENE DERIVATIVES, AND FLUORENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219380-A1 | Dibenzofuran Derivatives, Dibenzothiophene Derivatives and Fluorene Derivatives | ZYX, F3, YBX1 | HTR7 2870/4885HTR2B 1864/4885GPR3 1586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.