SCHEMBL4359049

SCHEMBL4359049

FC1c2ccccc2-c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.46
HTR2A P28223 2/20 0.46
HTR7 P34969 1/20 0.44
HTR2B P41595 1/20 0.44
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
NCOR2 Q9Y618 1/20 0.39
POLB P06746 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
ACHE P22303 3/20 0.37
BCHE P06276 2/20 0.37
CHRM2 P08172 1/20 0.37
HTR1A P08908 1/20 0.37
ADRA2A P08913 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29797969 1.00 GPR3 (0.46) GPR3HTR2AHTR7HTR2BHDAC3
SCHEMBL30829186 0.83 MEN1 (0.35) GPR3HTR2AHTR7HTR2BKMT2A
SCHEMBL10019068 0.82 ALDH1A1 (0.50) GPR3HTR2AHTR7HTR2BPOLB
SCHEMBL7562005 0.81 GPR3 (0.46) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL11199828 0.80 HTR7 (0.49) GPR3HTR2AHTR7HTR2BPOLB
SCHEMBL19934228 0.78 GPR3 (0.34) GPR3HTR2AHTR7HTR2BHDAC3
SCHEMBL19926520 0.78 MEN1 (0.42) HTR7HTR2BNCOR2POLBCYP1A2
SCHEMBL9811069 0.77 PPIA (0.43) GPR3HTR2ACYP19A1
SCHEMBL5613617 0.76 GPR3 (0.33) GPR3HTR2AHTR7HTR2BHDAC3
SCHEMBL23552340 0.75 PDK2 (0.42) GPR3HTR2AHTR7HTR2BACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110016002-B Fluorine-containing fluorene photoinitiator and application thereof 常州强力先端电子材料有限公司 2023-03-14 CN claimed
US-9210765-B2 Electronic device and electronic equipment provided with the electronic device SEIKO EPSON CORPORATION (JP) 2015-12-08 US claimed
JP-6342655-A None JP disclosed
CN-119403840-A Photocurable composition, method for producing cured film, solid-state imaging element, image display device, and radical polymerization initiator 富士胶片株式会社 2025-02-07 CN disclosed
CN-119212498-A Display panel, manufacturing method of display panel and display device 绵阳惠科光电科技有限公司 2024-12-27 CN disclosed
CN-115521195-B Preparation method of fluorene formaldehyde compound 上海如鲲新材料股份有限公司 2024-01-26 CN disclosed
CN-114507336-B Fluorine-containing near infrared absorption conjugated polymer and preparation method thereof 常州大学 2023-08-22 CN disclosed
CN-115521195-A Preparation method of fluorene formaldehyde compound 上海如鲲新材料股份有限公司 2022-12-27 CN disclosed
CN-115508298-A High-sensitivity aqueous singlet oxygen nano probe based on DPBF, preparation method and application 常州大学 2022-12-23 CN disclosed
CN-112888682-A Heteroaryl aminoquinolines and analogs 拜耳公司 2021-06-01 CN disclosed
WO-2020189576-A1 CRYSTAL OF HETEROCYCLIC AMIDE COMPOUND AND METHOD FOR PRODUCING SAME 日産化学株式会社 2020-09-24 WO disclosed
US-20090026925-A1 Electronic Device and Electronic Equipment Provided with the Electronic Device SEIKO EPSON CORPORATION (JP) 2009-01-29 US disclosed
CN-1207810-C Nonaqueous electrolyte and lithium secondary battery using the electrolyte MITSUI CHEMICALS INC (JP) 2005-06-22 CN disclosed
CN-1430306-A Nonaqueous electrolyte and lithium secondary battery using the electrolyte MITSUI CHEMICALS INC (JP) 2003-07-16 CN disclosed
JP-H06342655-A ELECTRODE AND BATTERY PROVIDED THEREWITH OSAKA GAS CO LTD 1994-12-13 JP disclosed
EP-0092385-B1 HYDANTOIN DERIVATIVES FOR USE IN INHIBITING ALDOSE REDUCTASE ACTIVITY, COMPOSITIONS THEREFOR AND PROCESS FOR PREPARING SPIRO-FLUOREN COMPOUNDS ALCON LABORATORIES, INC. (US) 1991-06-12 EP disclosed
EP-0311010-A2 Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1989-04-12 EP disclosed
US-4540700-A Treatment of diabetic complications with certain spiro-imidazolidine-diones ALCON LABORATORIES, INC. (US) 1985-09-10 US disclosed
WO-1983003543-A1 METHOD OF INHIBITING ALDOSE REDUCTASE ACTIVITY, COMPOSITIONS THEREFOR AND PROCESS FOR PREPARING SPIRO-FLUOROFLUOREN AND SPIRO-DIFLUOROFLUOREN COMPOUNDS ALCON LAB INC (US) 1983-10-27 WO disclosed
EP-0092385-A2 Hydantoin derivatives for use in inhibiting aldose reductase activity, compositions therefor and process for preparing spiro-fluoren compounds ALCON LABORATORIES, INC. (US) 1983-10-26 EP disclosed