Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.50 |
| ▸ | PTGIR | P43119 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30969690 | 0.94 | ALOX15 (0.65) | MAP4K4ALOX15ALDH1A1SMN1; SMN2FFAR1 | |
| SCHEMBL40485 | 0.94 | ALOX15 (0.65) | MAP4K4ALOX15ALDH1A1SMN1; SMN2FFAR1 | |
| SCHEMBL29240036 | 0.92 | ALOX15 (0.63) | MAP4K4ALOX15ALDH1A1SMN1; SMN2FFAR1 | |
| SCHEMBL27313420 | 0.92 | ALOX15 (0.63) | MAP4K4ALOX15ALDH1A1SMN1; SMN2FFAR1 | |
| Hydrochloric Acid SCHEMBL5903375 | 0.92 | ALOX15 (0.63) | MAP4K4ALOX15ALDH1A1SMN1; SMN2FFAR1 | |
| Hydrochloric Acid SCHEMBL11104858 | 0.92 | ALOX15 (0.63) | MAP4K4ALOX15ALDH1A1SMN1; SMN2FFAR1 | |
| SCHEMBL31134770 | 0.92 | ALDH1A1 (0.63) | MAP4K4ALOX15ALDH1A1SMN1; SMN2FFAR1 | |
| SCHEMBL27364334 | 0.92 | ALOX15 (0.63) | MAP4K4ALOX15ALDH1A1SMN1; SMN2FFAR1 | |
| Ammonia Solution, Strong SCHEMBL28895431 | 0.92 | ALOX15 (0.63) | MAP4K4ALOX15ALDH1A1SMN1; SMN2FFAR1 | |
| Potassium Ion SCHEMBL28331615 | 0.90 | ALOX15 (0.61) | MAP4K4ALOX15ALDH1A1SMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558567-B1 | NOVEL AMIDE COMPOUNDS WITH MCH ANTAGONISTIC EFFECT AND MEDICAMENTS COMPRISING SAID COMPOUNDS | BOEHRINGER INGELHEIM PHARMA (DE) | 2009-06-24 | — | — | EP | disclosed |
| US-7351719-B2 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2008-04-01 | — | — | US | disclosed |
| EP-1558567-A1 | NOVEL AMIDE COMPOUNDS WITH MCH ANTAGONISTIC EFFECT AND MEDICAMENTS COMPRISING SAID COMPOUNDS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-08-03 | — | — | EP | disclosed |
| US-20040152742-A1 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-08-05 | — | — | US | disclosed |
| WO-2004039764-A1 | NOVEL AMIDE COMPOUNDS WITH MCH ANTAGONISTIC EFFECT AND MEDICAMENTS COMPRISING SAID COMPOUNDS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-13 | — | — | WO | disclosed |
| EP-0324917-B1 | LOW PLATE-OUT POLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 1993-06-30 | — | — | EP | disclosed |
| US-4950782-A | Low plate-out polycarbonates | GENERAL ELECTRIC COMPANY (US) | 1990-08-21 | — | — | US | disclosed |
| EP-0324917-A1 | Low plate-out polycarbonates | GENERAL ELECTRIC COMPANY (US) | 1989-07-26 | — | — | EP | disclosed |
| US-4841015-A | Low plate-out polycarbonate end capped with phenoxy acetic acid | GENERAL ELECTRIC COMPANY (US) | 1989-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152742-A1 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | MCHR2, MCHR1, NPY1R | MAP4K4 3711/4885ALOX15 3121/4885ALDH1A1 4267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.