⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3281259 | 0.80 | — | — | |
| SCHEMBL18278528 | 0.72 | — | — | |
| SCHEMBL2065071 | 0.69 | — | — | |
| SCHEMBL15552632 | 0.69 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL24001175 | 0.65 | — | — | |
| SCHEMBL25043774 | 0.63 | TSHR (0.31) | — | |
| SCHEMBL3832305 | 0.63 | — | — | |
| SCHEMBL16975571 | 0.62 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL24517009 | 0.61 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL21779378 | 0.61 | SMN1; SMN2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473699-B2 | 3-cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and their use as antibacterial agents | ASTRAZENECA AB (SE) | 2009-01-06 | — | — | US | disclosed |
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| US-20050119292-A1 | 3-Cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and their use as antibacterial agents | ASTRAZENECA AB (SE) | 2005-06-02 | — | — | US | disclosed |