Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014067 | 0.90 | FAAH (0.71) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL3935806 | 0.89 | FAAH (0.78) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL4012855 | 0.87 | FAAH (0.79) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL3940445 | 0.87 | FAAH (0.84) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL3936102 | 0.86 | FAAH (0.77) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL3941135 | 0.86 | FAAH (1.00) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL3938587 | 0.86 | FAAH (0.93) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL3941324 | 0.85 | FAAH (0.73) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL3932859 | 0.85 | FAAH (0.78) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL3932602 | 0.85 | FAAH (0.78) | FAAHLMNAALDH1A1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |