Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.71 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011983 | 0.90 | FAAH (0.75) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL3935806 | 0.90 | FAAH (0.78) | FAAHHTR7HTR6LMNAALDH1A1 | |
| SCHEMBL3941324 | 0.86 | FAAH (0.73) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL4012855 | 0.85 | FAAH (0.79) | FAAHHTR7HTR6LMNAALDH1A1 | |
| SCHEMBL3934131 | 0.85 | FAAH (0.71) | FAAHHTR7HTR6LMNAALDH1A1 | |
| SCHEMBL3928556 | 0.85 | FAAH (0.75) | FAAHHTR7HTR6LMNAALDH1A1 | |
| SCHEMBL3940445 | 0.85 | FAAH (0.84) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL3929241 | 0.84 | FAAH (0.70) | FAAHHTR7HTR6LMNAALDH1A1 | |
| SCHEMBL3941999 | 0.84 | FAAH (0.72) | FAAHHTR7HTR6LMNAALDH1A1 | |
| SCHEMBL3945032 | 0.83 | FAAH (0.82) | FAAHLMNAALDH1A1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |