Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843771 | 0.84 | ALOX5 (0.50) | ALOX5MEN1GAAKMT2ACA12 | |
| SCHEMBL19024782 | 0.84 | KDM4E (0.64) | ALOX5MEN1GAAKMT2AKDM4E | |
| SCHEMBL6838077 | 0.83 | ALOX5 (0.51) | ALOX5MEN1GAAKMT2ACA12 | |
| SCHEMBL20480309 | 0.81 | KDM4E (0.48) | ALOX5MEN1GAAKMT2ACA12 | |
| SCHEMBL8493097 | 0.78 | CA12 (0.66) | MEN1GAAKMT2ACA12CA1 | |
| SCHEMBL6964091 | 0.78 | KDM4E (0.71) | KMT2AKDM4EAHRNPC1MAPT | |
| SCHEMBL20480355 | 0.76 | KDM4E (0.46) | ALOX5MEN1GAAKMT2ACA12 | |
| SCHEMBL8926694 | 0.76 | MEN1 (0.54) | MEN1GAAKMT2AKDM4EMAPT | |
| SCHEMBL4154259 | 0.75 | MAOB (0.55) | ALOX5MEN1KMT2ACA12CA1 | |
| SCHEMBL22617428 | 0.75 | MAOB (0.61) | ALOX5MEN1KMT2ARXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |