Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828909 | 0.81 | THRB (0.44) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL7823933 | 0.81 | MAPT (0.48) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL7828330 | 0.79 | KMT2A (0.43) | MEN1KMT2AMAPTGAALMNA | |
| SCHEMBL7824577 | 0.78 | MAPT (0.47) | MEN1KMT2AMAPTGAALMNA | |
| SCHEMBL7832320 | 0.78 | MAPT (0.42) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL9272800 | 0.78 | MAPT (0.47) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL7829191 | 0.78 | MAPT (0.47) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL7829801 | 0.77 | KMT2A (0.41) | MEN1KMT2AMAPTGAALMNA | |
| SCHEMBL8341922 | 0.76 | GPR35 (0.42) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL4012106 | 0.76 | ALOX5 (0.51) | MEN1KMT2AMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9124633-A | — | — | None | — | — | JP | disclosed |
| JP-H09124633-A | BENZOFURAN DERIVATIVE USEFUL AS BONE RESORPTION SUPPRESSING AGENT AND PRODUCTION THEREOF | FUJISAWA PHARMACEUT CO LTD | 1997-05-13 | — | — | JP | disclosed |