Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 16/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 14/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27786952 | 0.89 | NR1H2 (0.49) | NR1H2NR1H3RXRAESR1 | |
| SCHEMBL27765362 | 0.80 | CD38 (0.38) | NR1H2NR1H3ESR1RORC | |
| SCHEMBL4010226 | 0.78 | NR1H2 (0.57) | NR1H2NR1H3RXRA | |
| SCHEMBL4012475 | 0.74 | NR1H2 (0.58) | NR1H2NR1H3RXRA | |
| SCHEMBL27786951 | 0.74 | NR1H2 (0.46) | NR1H2NR1H3RXRA | |
| SCHEMBL4017313 | 0.74 | NR1H2 (0.70) | NR1H2NR1H3RXRA | |
| SCHEMBL27786950 | 0.73 | CD38 (0.41) | NR1H2NR1H3ESR1 | |
| SCHEMBL4010841 | 0.71 | RORC (0.40) | NR1H2NR1H3RXRAESR1RORC | |
| SCHEMBL4011954 | 0.70 | NR1H2 (0.73) | NR1H2NR1H3RXRA | |
| SCHEMBL4017110 | 0.69 | NR1H2 (0.57) | NR1H2NR1H3RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541751-A | Quinoline compounds | WYETH CORP (US) | 2009-09-23 | — | — | CN | claimed |
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |