SCHEMBL4012307

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4007300	0.86	CXCR4 (0.53)	CXCR4CA2CA1PTGER4ALDH1A1
	SCHEMBL4006291	0.86	CXCR4 (0.53)	CXCR4CA2CA1PTGER4ALDH1A1
	SCHEMBL4013046	0.81	ALDH1A1 (0.53)	CXCR4PTGER4ALDH1A1LMNA
	SCHEMBL4013129	0.81	ALDH1A1 (0.48)	CXCR4PTGER4ALDH1A1RORCLMNA
	SCHEMBL1413828	0.80	HTR6 (0.58)	CXCR4CA2CA1PTGER4ALDH1A1
	SCHEMBL4013097	0.80	TP53 (0.55)	CXCR4ALDH1A1LMNAHDAC1
	SCHEMBL4002900	0.78	CCR1 (0.49)	CXCR4PTGER4ALDH1A1RORCLMNA
	SCHEMBL13689663	0.78	CXCR4 (0.44)	CXCR4PTGER4ALDH1A1RORC
	SCHEMBL1413651	0.77	CXCR4 (0.54)	CXCR4CA2CA1ALDH1A1RORC
	SCHEMBL1413324	0.77	CXCR4 (0.54)	CXCR4CA2CA1PTGER4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.