Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3864113 | 0.99 | ACHE (0.69) | ACHESLC6A4KDM4ESMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL3868807 | 0.92 | ACHE (0.60) | ACHESLC6A4KDM4ESMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL3869830 | 0.85 | ACHE (0.51) | ACHESLC6A4KDM4ESMN1; SMN2POLB | |
| SCHEMBL4005576 | 0.85 | ACHE (0.76) | ACHESLC6A4RAB9A | |
| SCHEMBL4007712 | 0.85 | ACHE (0.76) | ACHESLC6A4RAB9A | |
| SCHEMBL4012422 | 0.85 | ACHE (0.76) | ACHESLC6A4RAB9A | |
| Hydrochloric Acid SCHEMBL3873753 | 0.84 | ACHE (0.75) | ACHESLC6A4 | |
| Hydrochloric Acid SCHEMBL3868611 | 0.84 | ACHE (0.75) | ACHESLC6A4 | |
| Hydrochloric Acid SCHEMBL3864656 | 0.84 | ACHE (0.75) | ACHESLC6A4 | |
| SCHEMBL4011375 | 0.84 | ACHE (0.65) | ACHESLC6A4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504393-B2 | Benzylamine analogues | BTG INTERNATIONAL LIMITED (GB) | 2009-03-17 | — | — | US | claimed |