Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 5/20 | 0.35 |
| ▸ | AKT2 | P31751 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1894707 | 0.89 | KDM4E (0.38) | KDM4EGAAALDH1A1GALR3HPGD | |
| SCHEMBL27771417 | 0.87 | KDM4E (0.44) | KDM4EGAAALDH1A1GALR3HPGD | |
| SCHEMBL2840920 | 0.85 | KDM4E (0.42) | KDM4EGAAALDH1A1GALR3HPGD | |
| SCHEMBL27792456 | 0.85 | KDM4E (0.41) | KDM4EGAAALDH1A1GALR3HPGD | |
| SCHEMBL27771400 | 0.84 | KDM4E (0.41) | KDM4EGAAALDH1A1GALR3HPGD | |
| SCHEMBL27771443 | 0.82 | ACHE (0.37) | KDM4EGAAALDH1A1GALR3HPGD | |
| SCHEMBL27792468 | 0.82 | CYP1A2 (0.45) | KDM4EGAAALDH1A1GALR3HPGD | |
| SCHEMBL27771371 | 0.76 | ACHE (0.38) | KDM4EGAAALDH1A1GALR3HPGD | |
| SCHEMBL12993748 | 0.76 | KDM4E (0.41) | KDM4EGAAALDH1A1GALR3HPGD | |
| SCHEMBL1895309 | 0.76 | KDM4E (0.41) | KDM4EGAAALDH1A1GALR3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101589037-A | Heteromonocyclic compounds and uses thereof | TAKEDA PHARMACEUTICAL (JP) | 2009-11-25 | — | — | CN | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |