Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4128501 | 0.77 | EPHX2 (0.68) | EPHX2 | |
| SCHEMBL19808153 | 0.60 | L3MBTL1 (0.63) | EPHX2L3MBTL1HSD11B1HSD17B10 | |
| SCHEMBL4016037 | 0.60 | EPHX2 (0.68) | EPHX2 | |
| SCHEMBL4128506 | 0.60 | EPHX2 (0.68) | EPHX2 | |
| SCHEMBL4016032 | 0.60 | EPHX2 (0.68) | EPHX2 | |
| SCHEMBL15807065 | 0.58 | — | — | |
| SCHEMBL3069167 | 0.56 | EPHX2 (0.70) | EPHX2L3MBTL1HSD11B1HSD17B10 | |
| SCHEMBL1193302 | 0.56 | L3MBTL1 (0.60) | EPHX2L3MBTL1HSD11B1HSD17B10 | |
| SCHEMBL14721307 | 0.55 | EP300 (0.47) | USP2HSD17B10 | |
| SCHEMBL7927463 | 0.55 | EP300 (0.47) | USP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086426-A2 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS FOR THE TREATMENT OF ENDOTHELIAL DYSFUNCTION | ARETE THERAPEUTICS, INC. (US) | 2009-07-09 | — | — | WO | claimed |