Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095812 | 0.75 | CHRM3 (0.41) | CHRM3PNMTHTR2CCHRM2CHRM4 | |
| SCHEMBL5600431 | 0.72 | PNMT (0.63) | CHRM3PNMTHTR2CHTR2AHTR2B | |
| SCHEMBL31018189 | 0.72 | PNMT (0.63) | CHRM3PNMTHTR2CHTR2AHTR2B | |
| SCHEMBL8411765 | 0.72 | HTR2A (0.46) | PNMTHTR2CHTR2AHTR2B | |
| Bromide SCHEMBL5708821 | 0.71 | PNMT (0.40) | CA2CA4PNMTCA1CA6 | |
| Hydrochloric Acid SCHEMBL31018191 | 0.71 | PNMT (0.61) | CHRM3PNMTHTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL3096808 | 0.71 | PNMT (0.61) | CHRM3PNMTHTR2CHTR2AHTR2B | |
| SCHEMBL11162952 | 0.68 | HTR2C (0.58) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL2994809 | 0.68 | HTR2C (0.35) | HTR2CHTR2AHTR2B | |
| SCHEMBL5022472 | 0.67 | PNMT (0.59) | CHRM3PNMTHTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |