Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013102 | 0.88 | PTPN1 (0.54) | MAPTMEN1KMT2ACDK2PTPN1 | |
| SCHEMBL29947857 | 0.76 | ALDH1A1 (0.52) | MAPTMEN1KMT2APTPN1ALOX15 | |
| SCHEMBL31538188 | 0.76 | MEN1 (0.50) | MAPTMEN1KMT2APTPN1S100A4 | |
| SCHEMBL27889093 | 0.75 | ALDH1A1 (0.51) | MAPTMEN1KMT2ACDK2PTPN1 | |
| SCHEMBL27905678 | 0.74 | KMT2A (0.53) | MAPTMEN1KMT2APTPN1MAOB | |
| SCHEMBL742927 | 0.73 | PIM1 (0.55) | MAPTMEN1KMT2AMAOBALOX15 | |
| SCHEMBL260788 | 0.72 | CYP1A2 (0.51) | MAPTS100A4ALOX15SMN1; SMN2POLB | |
| SCHEMBL29367937 | 0.72 | CYP1A2 (0.51) | MAPTS100A4ALOX15SMN1; SMN2POLB | |
| SCHEMBL29116218 | 0.72 | PTPN1 (0.50) | MAPTMEN1KMT2APTPN1MAOB | |
| SCHEMBL18575851 | 0.72 | ALDH2 (0.70) | MAPTMEN1KMT2AMAOBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |