Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013110 | 0.88 | MAPT (0.50) | PTPN1CDK2MAOBMAPTMEN1 | |
| SCHEMBL8549418 | 0.82 | HTR1A (0.56) | PTPN1CDK2MAPTMEN1KMT2A | |
| SCHEMBL4010048 | 0.76 | PTPN1 (0.57) | PTPN1MAOBMAPTMEN1KMT2A | |
| SCHEMBL4008145 | 0.75 | MAOB (0.54) | PTPN1CDK2MAOBMAPTMEN1 | |
| SCHEMBL4010077 | 0.73 | PTPN1 (0.81) | PTPN1MAOBMAPTMEN1KMT2A | |
| SCHEMBL2298324 | 0.73 | CYP1A2 (0.45) | MAPTPOLBATMS100A4ALDH1A1 | |
| SCHEMBL27279621 | 0.73 | MAOB (0.49) | MAOBMAPTKMT2ACA12MAOA | |
| SCHEMBL260788 | 0.72 | CYP1A2 (0.51) | MAPTPOLBATMS100A4ALDH1A1 | |
| SCHEMBL29367937 | 0.72 | CYP1A2 (0.51) | MAPTPOLBATMS100A4ALDH1A1 | |
| SCHEMBL27700646 | 0.72 | PTPN1 (0.65) | PTPN1MAOBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |