Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4015557 | 0.94 | POLB (0.49) | MAPTPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4015555 | 0.94 | POLB (0.49) | MAPTPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL13965458 | 0.87 | MEN1 (0.44) | MAPTPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4669271 | 0.84 | KMT2A (0.47) | MAPTPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4754381 | 0.84 | KMT2A (0.47) | MAPTPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4017819 | 0.84 | MEN1 (0.47) | MAPTPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4669514 | 0.83 | MEN1 (0.46) | MAPTPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4754393 | 0.83 | MEN1 (0.46) | MAPTPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4017504 | 0.83 | HPGD (0.53) | MAPTPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4017506 | 0.83 | HPGD (0.53) | MAPTPOLBKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014287-A1 | Use of cinnamic acid derivatives as modulators of an EP2 receptor | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-01-14 | — | — | EP | claimed |
| EP-2014287-A1 | Use of cinnamic acid derivatives as modulators of an EP2 receptor | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-01-14 | — | — | EP | disclosed |